陈曦;朱蓉;赵逵;

• 1:遵义医学院附属医院

摘要(Abstract)：

Ascl2是一个碱性/螺旋—环—螺旋转录因子,是Wnt信号通路的靶分子,仅表达于胎盘及小肠、大肠隐窝基底的Lgr5阳性的肠隐窝基底柱细胞(CBC细胞)。近来研究证实Ascl2是CBC成体肠干细胞的一个重要标记物,在维持结肠癌干/前体细胞的干细胞性方面发挥重要作用。本文对Ascl2与结肠癌的关系进行了综述。

关键词(KeyWords)： 干性标志物;Ascl2;Wnt信号通路;结肠癌

Abstract:

Keywords:

基金项目(Foundation): 贵州省高层次人才科研条件特助基金资助项目(TZJF-2011-32)

作者(Author): 陈曦;朱蓉;赵逵;

Email:

DOI:

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