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肠道正常菌群参与机体的物质代谢,营养物质的吸收合成,并能够促进生长发育,维持人体正常生理活动,其对胃肠道消化和免疫作用的发挥与肠杆菌、肠球菌、类杆菌和乳杆菌的关系密不可分。肠道黏膜免疫反应主要依靠肠腔内黏膜表面的免疫球蛋白(s Ig A为主)和淋巴细胞为主体的免疫活性细胞,共同完成肠道局部免疫。抗生素的使用可诱导肠道菌群失调,脑-肠轴参与了肠道菌群失调,其不仅可引起全身免疫疾病,还能导致肥胖、2型糖尿病及肠癌。
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基本信息:
DOI:
中图分类号:R363
引用信息:
[1]杨泽冉,辛毅,侯洁,等.肠道菌群失调及其相关疾病研究进展[J].山东医药,2016,56(01):99-101.
基金信息:
辽宁省教育厅科学基金项目(L2012325)